OptiMidas™ Microarray Platform Technology
Nirmidas OptiMidas™ Microarray Platform Technology is an all-in-one system for biomarker fluorescence detection. It combines plasmonic gold slides (pGOLD™ slides), MidaScan-IR™ or MidaScan™ Scanners, and multiplexed ELISA-like Assay kits to deliver biomarker detection of protein microarray and imaging assays.
OPTIMIDAS™ PGOLD™ Applications
Application areas include DNA, RNA, and Protein Microarrays, cell/tissue imaging, Immunohistochemistry (IHC), Single Molecule Imaging, and ELISPOT
Nirmidas provides all-inclusive kits, which may include dye-labeled detection antibodies, standard controls, diluents, and pGOLD™ biochips.
Fluorescence In Situ Hybridization (FISH), Förster resonance energy transfer (FRET), Fluorescence Recovery After Photobleaching (FRAP), Immunofluorescence Assays, Cellular Assays and more.
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"Validation of IgG, IgM multiplex plasmonic gold platform in French clinical cohorts for the serodiagnosis and follow-up of Toxoplasma gondii infection" Diagnostic Microbiology & Infectious Disease, 87, 213-218, 2017
"Diagnosis of Zika virus infection on a nanotechnology platform" Nature Medicine, advance online publication. 2017-03-06
"A plasmonic chip for biomarker discovery and diagnosis of type 1 diabetes” Nature Medicine, 20, 948-953, 2014.
"An Integrated Peptide-Antigen Microarray on Plasmonic Gold Films for Sensitive Human Antibody Profiling" PlosOne, Published online July, 2013.
"Multiplexed cytokine detection on plasmonic gold substrates with enhanced near-infrared fluorescence” Nano Research, 6 (2) 113-120 2013.
"Plasmonic substrates for multiplexed protein microarrays with femtomolar sensitivity and broad dynamic range" Nature Communications, 466, 1-9, 2011.
"Plasmonic Micro-Beads for Fluorescence Enhanced, Multiplexed Protein Detection with Flow Cytometry" Chem. Sci., 2014, DOI: 10.1039/C4SC01206B
Introduction to MidaScan™
All-in-one system for biomarker flurescence dection