pGOLD™ Slides

Plasmonic Gold Film Technology

Plasmonic gold (pGOLD™) microscope slides enable enhanced fluorescence by up to 100 fold in the wavelength range of 500 – 900nm

Plasmonic gold (pGOLD™) microscope slides enable enhanced fluorescence by up to 100 fold in the wavelength range of 500 – 900nm

Plasmonic gold allows for a significant improvement in signal-to-noise ratio, surpassing other substrates and beads by up to 100 fold in sensitivity and dynamic range. Plasmonic gold (pGOLD™) substrates and beads are useful for fluorescence and Raman based cellular imaging and molecular assays. Our pGold technology:

  • suppresses or blocks background signals
  • enables multi-color imaging
  • requires no additional assay steps
  • is compatable with standard cellular imaging, microarrays, and flow cytometric assay steps an equipment

pGOLD™, our innovative signal amplifying platform, originated from Stanford University and was published in Nature Communication and Nature Medicine. This technology is nano-engineered and uses a near-infrared enhanced fluorescence detection platform. The high sensitivity of the pGOLD™ technology has already be displayed in a novel diagnosis of Type 1 Diabetes; with pGOLD™, Type 1 Diabetes, while in its early stages, can be quickly and easily detected in hospitals around the world.

pGold Slides Product

Plasmonic gold (pGOLD™) substrates and beads reply on Nanoscience principles, such as nanogap enhanced excitation field strength and reduction in radiative lifetime of molecular excited states, to significantly increase the fluorescence emission of various fluorophores on the substrates.

The fluorescence enhancement is in the wavelength range of 500 – 900nm for Si based detectors and persists to > 1000 nm for infrared detectors. Substrates are compatible with fluorophores such as Cy3, Cy5, IRDye680, and IRDye800 dyes in this wavelength range and give the highest enhancement in the near-infrared window. The substrate can also enhance the Raman scattering signals of molecules by orders of magnitude.

Nirmidas pGold™ slides are available to purchase today. Email us at sales@nirmidas.com or fill in the form below.

Research Use Only

Research ready pGOLD™ slides, qty: 20, also available in qty: 5

Research ready pGOLD™ slides, qty: 20, also available in qty: 5

Applications

  • Protein (Cytokine/antibody/antigen) detection
  • DNA/RNA detection
  • cfDNA/CTC/exosomes analysis
  • Cell/tissue imaging
  • Multi-color imaging
  • Liquid Biopsy

Learn More about pGOLD Slides

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Introduction to Plasmonic Technology (pGOLD™)

introduction to Plasmonic Technology

Broad florescence enhancement due to unique gold structure, applicable to various flat and curved surfaces

learn more about Nirmidas pgold slides

Applying pGOLD™ to Multiplexed Autoantibody Dectection vs. Nitrocellulose and glass, Ovarian Cancer Biomarker CA125 detection, and more.